https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis, and APP regulation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45196 Wed 26 Oct 2022 15:23:03 AEDT ]]> A Novel Role of PP2A Methylation in the Regulation of Tight Junction Assembly and Integrity https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52191 Wed 15 May 2024 15:47:17 AEST ]]> The acute postprandial response of homocysteine to multivitamin and mineral supplementation with a standard meal is not impaired in older compared to younger adults https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52898 Tue 31 Oct 2023 15:45:21 AEDT ]]> Dietary intake and food sources of one-carbon metabolism nutrients in preschool aged children https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35858 Thu 21 Oct 2021 12:45:46 AEDT ]]> The role of protein phosphatase 2A in Alzheimer’s disease pathogenesis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36011 Thu 17 Jun 2021 16:06:18 AEST ]]> Methyl-donor and cofactor nutrient intakes in the first 2-3 years and global DNA methylation at age 4: a prospective cohort study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32077 0.05). Global DNA methylation levels in males were significantly higher than in females (median %5-mC: 1.82 vs. 1.03, males and females respectively, (P < 0.05)). Conclusion: No association was found between the intake of one-carbon metabolism nutrients during the early postnatal period and global DNA methylation levels at age four years. Higher global DNA methylation levels in males warrants further investigation.]]> Mon 23 Sep 2019 11:18:49 AEST ]]> Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52534 Mon 16 Oct 2023 14:56:57 AEDT ]]> Global DNA methylation and cognitive and behavioral outcomes at 4 years of age: a cross-sectional study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40011 p > .05), though the estimates of effect were consistently negative. Global DNA methylation levels in males were significantly higher than in females (median %5mC: 1.82 vs. 1.03, males and females, respectively, (p < .05)). Conclusion: No association was found between global DNA methylation and child cognition and behavior; however given the small sample, this study should be pooled with other cohorts in future meta-analyses.]]> Fri 15 Jul 2022 10:09:55 AEST ]]>